List D: Permanent impairment/Early intervention, under 7 years. No further assessment required.

Synonyms for conditions are also shown (e.g. condition / synonym / synonym)

Conditions primarily resulting in Neurological  impairment

Chromosomal abnormalities resulting in permanent impairment

  • Global Developmental Delay
  • Aicardi syndrome
  • Aicardi-Goutières syndrome
  • Angelman syndrome
  • CHARGE syndrome
  • Cockayne syndrome/ Types I and Type II / Cerebro-oculo-faciao-skeletal (COFS) syndrome/ Pena Shokeir syndrome Type II / Weber-Cockayne syndrome/ Neill-Dingwall syndrome
  • Coffin-Lowry syndrome
  • Cohen syndrome
  • Cornelia de Lange syndrome
  • Cri du Chat syndrome
  • Dandy-Walker syndrome
  • DiGeorge syndrome/ 22q11.2 deletion syndrome/ Velocardiofacial syndrome/ Shprintzen syndrome/ Conotruncal anomaly face syndrome
  • Down syndrome/ Trisomy 21
  • Edwards syndrome/ Trisomy 18
  • Fragile X syndrome
  • Kabuki syndrome
  • Lesch-Nyhan syndrome/ Nyhan’s syndrome/ Kelley-Seegmiller syndrome/ Juvenile gout
  • Leigh syndrome/ Leigh’s disease/ subacute necrotizing encephalomyelopathy
  • Menkes disease
  • Patau syndrome/ Trisomy 13
  • Prader-Willi syndrome
  • Rett syndrome
  • Seckel syndrome/ microcephalic primordial dwarfism/ Harper’s syndrome/ Virchow-Seckel dwarfism
  • Smith-Lemli-Optiz syndrome
  • Smith-Magenis syndrome
  • Sturge-Weber syndrome
  • Trisomy 9
  • Tuberous sclerosis
  • Williams syndrome
  • Wolf-Hirschhorn syndrome.

Conditions primarily resulting in neurological impairment

Systemic atrophies primarily affecting the central nervous system

  • Friedrich’s ataxia
  • Hereditary spastic paraplegia/ Infantile-onset ascending hereditary spastic paralysis/ L1 syndrome/ spastic paraplegias types 2 and 11
  • Louis-Bar syndrome/ Ataxia-telangiectasia
  • Niemann-Pick disease (Types A and C)
  • Progressive bulbar palsy of childhood/ Fazio-Londe disease.

The following spinal muscular atrophies

  • Spinal muscular atrophy Type I/ Werdnig Hoffmann disease/ infantile SMA
  • Spinal muscular atrophy Type II/ Dubowitz disease
  • Spinal muscular atrophy Type III Kugelberg-Welander disease/ juvenile SMA
  • Spinal muscular atrophy lower extremity dominant/ SMA-LED
  • X-linked spinal muscular atrophy.

Extrapyramidal and movement disorders

  • Hallervorden-Spatz syndrome / Pantothenate kinase-associated neurodegeneration (PKAN)/ neurodegeneration with brain iron accumulation 1 (NBIA 1)
  • Alpers disease/ Alpers syndrome/ Grey-matter degeneration/ Progressive sclerosing poliodystrophy/ Progressive infantile poliodystrophy
  • Demyelinating diseases of the central nervous system
  • Adrenoleukodystrophy / X-linked childhood cerebral form
  • Alexander disease
  • Canavan disease
  • Krabbe disease/ Globoid cell leukodystrophy
  • Pelizaeus-Merzbacher disease.

Episodic and paroxysmal disorders

  • Lennox-Gastaut syndrome/ Lennox syndrome
  • West’s syndrome.

Polyneuropathies and other disorders of the peripheral nervous system

  • Dejerine-Sottas disease/ Dejerine-Sottas syndrome/ Dejerine-Sottas neuropathy/ progressive hypertrophic interstitial polyneuropathy of childhood/onion bulb neuropathy
  • Infantile Refsum disease.

Conditions primarily resulting in physical impairment

  • Amputation
  • Diamond-Blackfan anaemia
  • Epidermolysis bullosa
  • Harlequin type icthyosis
  • Hay Wells syndrome/ ankyloblepharon/ ectodermal dysplasia/ clefting [AEC] syndrome
  • Joint or limb deformities resulting in impaired mobility
  • Juvenile arthritis/ Stills Disease
  • Osteogenesis imperfecta
  • Sjogren Larsson syndrome.

Diseases of myoneural junction and muscle

  • Congenital muscular dystrophy
  • Congenital myotonia / Thomsens disease/ Becker myotonia
  • Distal muscular dystrophy
  • Duchenne muscular dystrophy
  • Emery-Dreifuss muscular dystrophy
  • Facioscapulohumeral muscular dystrophy
  • Myotubular myopathy
  • Oculopharyngeal muscular dystrophy
  • Paramyotonia Congenita.

Cerebral palsy and other paralytic syndromes

  • Cerebral palsy
  • Diplegia
  • Hemiplegia
  • Monoplegia
  • Paraplegia
  • Quadriplegia
  • Tetraplegia.

Conditions resulting in sensory and/or speech impairment

  • Permanent blindness in both eyes, diagnosed and assessed by an ophthalmologist as follows:
  • Corrected visual acuity (extent to which an object can be brought into focus) on the Snellen Scale must be less than or equal to 6/60 in both eyes; or
  • Constriction to within 10 degrees or less of arc of central fixation in the better eye, irrespective of corrected visual acuity (i.e. visual fields are reduced to a measured arc of 10 degrees or less); or
  • A combination of visual defects resulting in the same degree of visual impairment as that occurring in the above points.
  • (An optometrist report is not sufficient for NDIS purposes.)
  • Deafblindness confirmed by ophthalmologist and audiologist and assessed as resulting in permanent and severe to total impairment of visual function and hearing.

Conditions resulting in multiple types of impairment

  • Aceruloplasminemia
  • Addison-Schilder disease/ Adrenoleukodystrophy /
  • Albinism
  • Arginosuccinic aciduria
  • Aspartylglucosaminuria
  • Cerebrotendinous xanthomatosis/ cerebral cholesterosis
  • Congenital cytomegalovirus infection
  • Congenital hypothyroidism
  • Congenital iodine-deficiency syndrome /cretinism
  • Congenital rubella syndrome
  • Galactosaemia with long term learning disabilities and neurological impairment
  • Glycine encephalopathy/ non-ketotic hyperglycinaemia
  • GM1 gangliosidosis
  • Hartnup disease
  • Homocystinuria
  • Lowe syndrome/ Oculocerebrorenal syndrome
  • Mannosidosis
  • Menkes disease
  • Mucolipidosis II / I-cell disease
  • Mucolipidosis III / pseudo-Hurler polydystrophy
  • Mucolipidosis IV
  • Neuronal ceroid lipofuscinosis
  • Niemann-Pick disease
  • Phenylketonuria
  • Pyruvate carboxylase deficiency
  • Pyruvate dehydrogenase deficiency
  • Sialidosis
  • Sulfite oxidase deficiency.

The following mucopolysaccharidoses

  • Hurler syndrome/MPS1-H
  • Scheie syndrome/ MPS 1-S
  • Hurler-Scheie syndrome/ MPS 1 H-S
  • Hunter syndrome/ MPS II
  • San Fillipo syndrome/ MPS III
  • Morquio syndrome/ MPS IVA
  • Maroteaux-Lamy syndrome/ MPS VI
  • Sly syndrome/ MPS VII.

The following lysosomal storage disorders

  • Gaucher disease Types 2 and 3
  • Niemann-Pick disease (Types A and C)
  • Pompe disease
  • Sandhoff disease (infantile form)
  • Schindler disease (Type 1)
  • Tay-Sachs disease (infantile form).

Congenital conditions – cases where malformations cannot be corrected by surgery or other treatment and result in permanent impairment

  • Chiari malformation/Arnold-Chiari malformation
  • Congenital absence of limb(s)
  • Congenital hydrocephalus
  • Fetal alcohol spectrum disorder
  • Fetal hydantoin syndrome
  • Microcephaly
  • Spina bifida
  • VATER syndrome (VACTERL association).
This page current as of
27 October 2023
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